Generic Name: Domperidone

Description & Properties :
Motilat (Domperidone) is a dopamine antagonist with anti-emetic properties.Due to its weak crossing of the blood-brain barrier, it is
unlikely to produce central effects such as extrapyramidal reactions or drowsiness.
Motilat increases the duration of antral and duodenal contractions and facilitates gastric emptying and regulates pyloric contractions.
It also increases oesophageal peristalsis and lower oesophageal sphincter pressure. Motilat restores normal motility & tone of the
upper gastrointestinal tract.
Motilat is indicated for the treatment of:
-The dyspeptic symptom complex which is often associated with delayed gastric emptying, gastro-oesophageal reflux and oesophagitis,
these symptoms include sensation of epigastric fullness, upper abdominal pain or discomfort, nausea with or without vomiting and
heartburn which might be associated with regurgitation of food.
– Eructation & flatulence
– Nausea and vomiting of functional, organic, infectious or dietetic origin as well as nausea & vomiting induced by radiotherapy or
chemotherapy. It is used for nausea and vomiting caused by levodopa or bromocriptine administered for the treatment of
Parkinson’s disease.
Presentation :
Motilat Tablets: Each tablet contains Domperidone 10 mg. Blister packs of 30 tablets & hospital packs of different sizes are available.
Motilat Suspension: Each 1 ml contains Domperidone 1 mg. Bottles of 100 & 200 ml.