CONCOR 5MG TAB 30’S

CONCOR 5MG 30 TABLETS
 
** Concor® 5 plus 30 film-coated tablets. Cardioselective beta-blocker and diuretic, antihypertensive.
** Composition: 1 film-coated tablet contains: Bisoprolol fumarate (2:1) 5 mg and Hydrochlorothiazide 12.5 mg
** Indications: – Arterial hypertension. – The combination preparation Concor 5/10 plus is recommended if monotherapy is not sufficiently effective.
** Contra-indications: – manifest heart failure. – shock. – 2nd or 3rd degree AV block. – sick sinus syndrome. – sinoatrial block. – bradycardia (resting pulse less than 50 beats/min before the start of therapy). – acidosis. – bronchial hyperresponsiveness (e.g. bronchial asthma). – late stages of peripheral circulatory disturbances. – concomitant administration of MAO inhibitors (exception: MAO-B inhibitors). – severe disturbances of kidney function (renal insufficiency with oliguria or anuria; creatinine clearance less than 30 mL/min and/or serum creatinine more than 1.8 mg/100mL. – acute glomerulonephritis. – coma and hepatic precoma. – refractory hypokalaemia. – severe hyponatraemia. – hypercalcaemia. – gout. – hypersensitivity to hydrochlorothiazide and other thiazides, sulphonamides, and beta-blockers. – children (no therapeutic experience).
** Special warnings and precuations for use: Patients with any of the following should be monitored closely: – 1st degree AV block. – mainfest or latent diabetes mellitus (severe hypoglycaemic conditions possible; regular monitoring of blood glucose). – prolonged periods of strict fasting and heavy physical strain (possibility of severe hypoglycemic conditions). – patients with phaeochromocytoma (tumor of the adrenal medulla) (Concor plus should not be administered until after alpha-blockade). – hypovolaemia. – cerebral sclerosis. – coronary sclerosis. – impaired kidney function of mild degree and co-existing impairment of liver function (dose adjustment). – Prinzmetal’s angina. – In patients with psoriasis in their psersonal or family history medication containing beta-blockers should only be prescribed if the risk/benefit has been carefully evaluated. – Beta blockers can increase the sensitivity to allergens and the severity of anaphylactic reactions. Therefore, Concor plus should only be prescribed if considered essential in patients with a history of severe hypresensitivity reactions and in patients undergoing desensitisation therapy (beware of of excessive anaphylactic reactions).
** Psology and method of administration:
– The treatment of high blood pressure should principally be started with low doses of a single active substance and then increased gradually. – The fixed combination of Concor 5/10 plus consisting of bisoprolol and hydrochlorothiazide should be administered only if the blood pressure could not be normalised by the individual active substances or else excessive adverse reactions had occured at high doses. The following apply as guidelines:
# Arterial hypertension: – Normally 1× 1 film-coated tablet of Concor 5 plus (equivalent to 5 mg bisoprolol and 12.5 mg hydrochlorothiazide) daily. If the blood pressure is only inadequately reduced the dose may be increased to 1 × 2 film-coated tablets of Concor 5 (equivalent to 10 mg bisoprolol and 25 mg hydrochlorothiazide) or 1 film-coated tablet of Concor 10 plus once daily. In co-existing impairment of kidney or liver function, the elimination of the HCT component of Concor 5/10 plus is reduced, so that preference may be to the lower dose form.
# Mode and duration of administration: – The film-coated tablets are to be swallowed whole with the breakfast with some liquid. – There is no limit to the duration of administration. It depends upon the nature and severity of the disease. – After long-term therapy – particularly in the presence of ischaemic heart disease Concor 5/10 plus should be discontinued gradually (i.e. over 7-10 days), since an abrupt withdrawal may lead to an acute deterioration of the patient’s condition.
** Dosage as directed by the physician. By prescription only.
** Store below 25 degrees C, in a dry place, protected from moisture.
Product Description
Concor Tablet is an antihypertensive which is used alone or in combination with other agents to lower the elevated blood pressure. It is administered with caution in the patients with lung disease
This drug is prescribed to patients with high blood pressure (normal blood pressure for adult’s is usually 120/80 mmHg) and to patients with mild to moderate chronic heart failure as Concor 5mg Tablet 14.0 'S is very efficient in decreasing risk of future heart illnesses.Hypertension left untreated can cause severe damage to the brain,heart,kidney,blood vessels and other body organs.
Concor 5mg Tablet 14.0 'S belongs to a group of chemicals known as beta blockers;which work on the heart muscles,to lower the number of contractions (heartbeats) per minute of the heart and thereby,making sure that the flow and release of blood from the heart continues normally.Concor 5mg Tablet 14.0 'S also works on the human blood vessels and helps in bringing raised blood pressure levels to normal by preventing the narrowing of vessels so that blood may flow with ease through them and reach all the organs in the body.
A tablet per day is commonly prescribed to patients to be taken either with or without food.Concor 5mg Tablet 14.0 'S is to be taken regularly,preferably at the same time each day to help the patient remember their daily dose.The patient ought to discuss with their physician before ceasing intake of the medicine even if the patient is no longer suffering from common symptoms of the hypertension as ceasing the intake of the medicine has reported in cases of rebound hypertension (the re-emergence of high blood pressure),therefore,physicians taper of the Concor 5mg Tablet 14.0 'S’s dosage before completely stopping it.
Concor 5mg Tablet 14.0 'S might show mild side effects such as fatigue,dizziness and skin rash which resolve on their own in a few days' time.Concor 5mg Tablet 14.0 'S is not safe to be prescribed to pregnant or lactating mothers;nor is it safe for individuals under the age of 18 years.Dosage of Concor 5mg Tablet 14.0 'S is dependent upon each individual patient’s weight,the stage of their illness,the patient’s response to treatment and any medical conditions the patient may be suffering along with hypertension.While undergoing treatment with Concor 5mg Tablet 14.0 'S,the physician may ask the patient to get certain lab work done periodically to monitor the effects of the drug on the patient’s body and monitor the patient’s blood pressure,blood glucose levels,liver functions and potassium levels.Accordingly the physician may change the dosage of the drug prescribed.
Indications
Concor 5mg Tablet 14.0 'S can be used to treat:
Hypertension 
Reduce the risk of stroke 
Heart attack 
Kidney problems
How Does Concor 5mg Tablet 14.0 'S Work
This drug belongs to a group of drugs known as Beta Blockers.Epinephrine is a natural hormone found in the body that works by narrowing the blood vessels in the human body as well as triggering other sympathetic responses in the body.Concor 5mg Tablet 14.0 'S works by inhibiting epinephrine from performing its duties by blocking beta receptors and therefore preventing the narrowing of blood vessels and aiding the free and proper flow of blood to the organs and through the blood vessels.
 
Hypertension, angina pectoris, congestive heart failure.
وصف المنتج
الذبحة الصدرية, ارتفاع ضغط الدم، وقصور القلب الاحتقاني