* Composition: Each film-coated tablet contains:
  Metformin hydrochloride 1000 mg (equivalent to metformin base 780 mg).
* Therapeutic indications: As an adjunct to adequate dietary management, GLUCOPHAGE 1000 mg is an oral antidiabetic agent
  (biguanide) intended for the treatment of adult diabetes. In some cases, it may be used in association with insulin.
* Pediatic indication: In children from 10 years of age and adolescents, GLUCOPHAGE 1000 mg, film-coated may be used
  as monotherapy or in combination with insulin.
* Contra-indications: This drug MUST NEVER BE USED in the following cases:
– Known hypersensitivity to metformin hydrochloride or any of the product ingredients,
– Severe destabilisation of diabetes (ketoacidosis),
– Renal insufficiency, even if moderate (impairment of kidney function with increased blood creatinine levels),
– Infectious diseases (respiratory tract infection, urinary tract infection),
– During the two days following an X-ray examination involving the use of iodinated contrast media (for example,
  intravenous urography, angiography),
– Heart failure, respiratory insufficiency,
– Hepatic insufficiency (impaired liver function),
– Persistent diarrhea, recurrent vomiting,
– Excessive consumption of alcoholic beverages,
– During breast-feeding.
* Dosage:
– The dosage of GLUCOPHAGE 1000 mg is determined by your doctor on an individual basis according to the results
  of laboratory blood glucose measurement.
– In general, the average dosage is 2 tablets per day (taken with or after meals).
– For children from 10 years of age and adolescents, the maximum recommended dose of metformin is 2 g daily, taken
  as 2 or 3 divided doses.
– Frequency & time at which the drug should be taken: Swallow the tablets without chewing during or at the end of meals.
  For example, for a dosage of 2 tablets daily take 1 tablet with breakfast and 1 tablet with your evening meal.
– Duration of treatment: Glucophage must be taken daily without interruption, except if specifically indicated by your doctor.
  If you have forgotten to take a GLUCOPHAGE 1000mg film-coated tablet: Take the next dose at the usual time. Do not double
  the dose of Glucophage 1000mg film-coated tablets.
  If you have taken more GLUCOPHAGE 1000mg film-coated tablets than indicated: Consult your doctor or pharmacist immediately.
* Special warnings: Vomiting, abdominal pain accompanied by muscle cramps and/or a general feeling of malaise with severe
  fatigue occuring during therapy may be signs of serious destablisation of your diabetes (diabetic ketoacidosis or lactic acidosis)
  requiring specific treatment. If this occurs, you should stop taking Glucophage immediately and consult your doctor promptly.
* For Adults – With Meals.
* To be used only on medical advice.
* Store below 25 degrees C.
* MINAPHARM. Under Licence of: Merck Sante France (MERCK SERONO).